World

Is An Oral AntiViral Drug The Answer To COVID-19 Treatment?
India bans 156 combination drugs

Scientists have found a new experimental antiviral drug MK-4482, which could help in the treatment of the SARS-CoV-2 infection.

It significantly decreased the levels of virus and disease damage in the lungs of hamsters treated for the infection, according to a new study from National Institutes of Health scientists, Science Daily reported.

MK-4482, delivered orally, is now in human clinical trials.

In their study, published in the journal ‘Nature Communications’, the scientists found MK-4482 treatment effective when provided up to 12 hours before or 12 hours after infecting the hamsters with SARS-CoV-2.
These data suggest that MK-4482 treatment could potentially mitigate high-risk exposures to SARS-CoV-2, and might be used to treat established SARS-CoV-2 infection alone or possibly in combination with other agents.
The University of Plymouth in the United Kingdom collaborated on these most recent studies. The project involved three groups of hamsters: a pre-infection treatment group; a post-infection treatment group; and an untreated control group, the report said.
For the two treatment groups, scientists administered MK-4482 orally every 12 hours for three days. At the conclusion of the study, the animals in each of the treatment groups had 100 times less infectious virus in their lungs than the control group.
Animals in the two treatment groups also had significantly fewer lesions in the lungs than the control group.
Merck and Ridgeback Biotherapeutics are now jointly developing and evaluating MK-4482 as a potential COVID-19 treatment. The drug is in Phase 2 and 3 human clinical studies.
OB Bureau
Share
Published by
OB Bureau
4 years ago

Recent Posts

Champions Trophy: Virat Kohli (100*) Masterclass Floors Pakistan; Check Milestones He Conquered

Dubai: ODI cricket, Pakistan – they bring out the best in Virat Kohli. The Dubai… Read More

3 hours ago

3 Arrested For Looting Govt Official By Using Toy Gun In Odisha

Cuttack: Three criminals were arrested by Choudwar police in Odisha’s Cuttack district for allegedly looting… Read More

3 hours ago

ISL: 10-Man Odisha FC Go Down 0-1 To Toppers Mohun Bagan Via Injury-Time Goal

Kolkata: Odisha FC fought gallantly in the lion’s den but finally returned empty-handed. Up against league… Read More

3 hours ago

Caught Using AI To Solve Maths Problem, Class X Board Exam Candidate Loses A Year!

Kolkata: A West Bengal secondary board exam (Madhyamik) candidate recently took Artificial Intelligence (AI) to… Read More

4 hours ago

4th Batch Of Illegal Immigrants Back: 12 Indians Deported From US To Panama Arrive At Delhi’s IGI Airport

New Delhi: A fourth batch of Indian nationals deported from the US arrived at Indira… Read More

4 hours ago

Record 6.82 Lakh Olive Ridley Turtles Visit Odisha’s Rushikulya River Mouth For Mass Nesting

Berhampur: Rushikulya river mouth in Odisha’s Ganjam district has emerged as a major rookery for… Read More

5 hours ago