Coronavirus

Russian COVID Vaccine ‘Sputnik’ Triggers Immune Response: Lancet

New Delhi: Going by the results from the early-stage clinical trials of Sputnik, the Russia registered world’s first COVID-19 vaccine, there is hope. The trials show that formulations of a two-part vaccine have a good safety profile with no serious adverse events detected over 42 days.

The results were published in ‘The Lancet’. The trials also confirmed that the vaccine induces antibody responses in all participants within 21 days, reported The New Indian Express (TNIE).

The success of Sputnik V, which is set to enter into a late-stage trial involving 40,000 individuals and would also be given to high-risk and consenting individuals beginning October, could have implications for India, the report added.

The Russian government is keen to get the vaccine tried in India as part of the phase 3 trial. It also wants Indian manufacturers to mass-produce the vaccine.

Limitations in the research

  • It had a short follow-up of 42 days
  • It was a small study
  • Some parts of the phase 1 trials included only male volunteers
  • There was no control vaccine
  • It included fairly young volunteers in their 20s and 30s

TNIE quoted researchers as saying that more research is needed to evaluate the vaccine in different populations, including older age groups, individuals with underlying medical conditions, and people in at-risk groups.

OB Bureau

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